Global versus factor‐related impression of severity in Parkinson's disease: A new clinimetric index (CISI‐PD)
Identifieur interne : 003419 ( Main/Exploration ); précédent : 003418; suivant : 003420Global versus factor‐related impression of severity in Parkinson's disease: A new clinimetric index (CISI‐PD)
Auteurs : Pablo Martínez-Martín [Espagne] ; M. João Forjaz [Espagne] ; Esther Cubo [Espagne] ; Belén Frades [Espagne] ; Jesús De Pedro Cuesta [Espagne]Source :
- Movement Disorders [ 0885-3185 ] ; 2006-02.
English descriptors
- KwdEn :
- Aged, Aged, 80 and over, Clinical Global Impression of Severity, Clinical Impression of Severity Index for Parkinson's Disease, Cognition Disorders (classification), Cognition Disorders (diagnosis), Cross-Sectional Studies, Disability Evaluation, Humans, Linear Models, Male, Middle Aged, Neurologic Examination (statistics & numerical data), Outcome Assessment (Health Care) (statistics & numerical data), Parkinson Disease (classification), Parkinson Disease (diagnosis), Parkinson's disease, Reproducibility of Results, assessment, clinimetric index.
- MESH :
- classification : Cognition Disorders, Parkinson Disease.
- diagnosis : Cognition Disorders, Parkinson Disease.
- statistics & numerical data : Neurologic Examination, Outcome Assessment (Health Care).
- Aged, Aged, 80 and over, Cross-Sectional Studies, Disability Evaluation, Humans, Linear Models, Male, Middle Aged, Reproducibility of Results.
Abstract
In Parkinson's disease (PD), the Clinical Global Impression of Severity (CGIS) is often used as an additional outcome in clinical trials. It is hypothesized that this measure summarizes clinical assessment and is mainly influenced by the rating of four domains, namely, motor signs, disability, motor complications, and cognitive impairment. Ratings of these four factors were combined to form a new Clinical Impression of Severity Index for Parkinson's Disease (CISI‐PD). A sample of 150 PD patients was evaluated using the following scales: Hoehn and Yahr staging, Schwab and England scale, Unified Parkinson's Disease Rating Scale, Scales for Outcomes in Parkinson's Disease–Motor Scale, CGIS, and CISI‐PD. The results show that the CGIS is closely related to the above‐mentioned measures (r = 0.49–0.89). CISI‐PD correlation with these scales was very similar (r = 0.55–0.91), to the extent that the difference between corresponding coefficients was systematically less than 0.10. A multiple regression model showed that 92% of the CIGS variance was explained by the four CISI‐PD items. Finally, the CISI‐PD displayed adequate psychometric properties, with satisfactory internal consistency (α = 0.90) and convergent (r > 0.75) and known‐groups validity. The CISI‐PD is a valid and reliable measure that expands the information obtained via the CGIS. © 2005 Movement Disorder Society
Url:
DOI: 10.1002/mds.20697
Affiliations:
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Disord.</title><idno type="ISSN">0885-3185</idno><idno type="eISSN">1531-8257</idno><imprint><publisher>Wiley Subscription Services, Inc., A Wiley Company</publisher><pubPlace>Hoboken</pubPlace><date type="published" when="2006-02">2006-02</date><biblScope unit="vol">21</biblScope><biblScope unit="issue">2</biblScope><biblScope unit="page" from="208">208</biblScope><biblScope unit="page" to="214">214</biblScope></imprint><idno type="ISSN">0885-3185</idno></series><idno type="istex">9892F043545DA0CD57FAAE6C66B5B53A0956F4B1</idno><idno type="DOI">10.1002/mds.20697</idno><idno type="ArticleID">MDS20697</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0885-3185</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Aged, 80 and over</term><term>Clinical Global Impression of Severity</term><term>Clinical Impression of Severity Index for Parkinson's Disease</term><term>Cognition Disorders (classification)</term><term>Cognition Disorders (diagnosis)</term><term>Cross-Sectional Studies</term><term>Disability Evaluation</term><term>Humans</term><term>Linear Models</term><term>Male</term><term>Middle Aged</term><term>Neurologic Examination (statistics & numerical data)</term><term>Outcome Assessment (Health Care) (statistics & numerical data)</term><term>Parkinson Disease (classification)</term><term>Parkinson Disease (diagnosis)</term><term>Parkinson's disease</term><term>Reproducibility of Results</term><term>assessment</term><term>clinimetric index</term></keywords><keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>Cognition Disorders</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Cognition Disorders</term><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="statistics & numerical data" xml:lang="en"><term>Neurologic Examination</term><term>Outcome Assessment (Health Care)</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Aged, 80 and over</term><term>Cross-Sectional Studies</term><term>Disability Evaluation</term><term>Humans</term><term>Linear Models</term><term>Male</term><term>Middle Aged</term><term>Reproducibility of Results</term></keywords></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">In Parkinson's disease (PD), the Clinical Global Impression of Severity (CGIS) is often used as an additional outcome in clinical trials. It is hypothesized that this measure summarizes clinical assessment and is mainly influenced by the rating of four domains, namely, motor signs, disability, motor complications, and cognitive impairment. Ratings of these four factors were combined to form a new Clinical Impression of Severity Index for Parkinson's Disease (CISI‐PD). A sample of 150 PD patients was evaluated using the following scales: Hoehn and Yahr staging, Schwab and England scale, Unified Parkinson's Disease Rating Scale, Scales for Outcomes in Parkinson's Disease–Motor Scale, CGIS, and CISI‐PD. The results show that the CGIS is closely related to the above‐mentioned measures (r = 0.49–0.89). CISI‐PD correlation with these scales was very similar (r = 0.55–0.91), to the extent that the difference between corresponding coefficients was systematically less than 0.10. A multiple regression model showed that 92% of the CIGS variance was explained by the four CISI‐PD items. Finally, the CISI‐PD displayed adequate psychometric properties, with satisfactory internal consistency (α = 0.90) and convergent (r > 0.75) and known‐groups validity. The CISI‐PD is a valid and reliable measure that expands the information obtained via the CGIS. © 2005 Movement Disorder Society</div></front></TEI><affiliations><list><country><li>Espagne</li></country><region><li>Communauté de Madrid</li></region><settlement><li>Madrid</li></settlement></list><tree><country name="Espagne"><region name="Communauté de Madrid"><name sortKey="Martinez Artin, Pablo" sort="Martinez Artin, Pablo" uniqKey="Martinez Artin P" first="Pablo" last="Martínez-Martín">Pablo Martínez-Martín</name></region><name sortKey="Cubo, Esther" sort="Cubo, Esther" uniqKey="Cubo E" first="Esther" last="Cubo">Esther Cubo</name><name sortKey="De Pedro Cuesta, Jesus" sort="De Pedro Cuesta, Jesus" uniqKey="De Pedro Cuesta J" first="Jesús" last="De Pedro Cuesta">Jesús De Pedro Cuesta</name><name sortKey="Forjaz, M Joao" sort="Forjaz, M Joao" uniqKey="Forjaz M" first="M. João" last="Forjaz">M. João Forjaz</name><name sortKey="Frades, Belen" sort="Frades, Belen" uniqKey="Frades B" first="Belén" last="Frades">Belén Frades</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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